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Lisa Alvarez-Cohen
- Chair of Civil & Environmental Engineering
- Fred and Claire Sauer Professor
- Faculty Scientist, Ecology Dept., Earth Sciences Division, Lawrence Berkeley National Laboratory
Mailing Address:
Civil and Environmental Engineering
760 Davis Hall
University of California
Berkeley, CA 94720-1710
Email:
chair@ce.berkeley.edu
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Phone:
(510) 643-8739
Fax:
(510) 643-5264
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Teaching and Research
Professor Alvarez-Cohen teaching duties include graduate and undergraduate courses in environmental microbiology, environmental biological processes, and environmental engineering. Current research areas include microbial ecology of bioremediation, biotransformation of environmental contaminants including chlorinated solvents, NDMA, 1,4-Dioxane and PBDEs; and genomic, transcriptomic, proteomic and isotopic evaluation of bioremediation communities.
Alvarez-Cohen Research Group


Ongoing research projects include:
Professor Alvarez-Cohen recently co-authored a textbook entitled Environmental Engineering Science,
available from John Wiley and Sons. Prof. Alvarez-Cohen, along with Prof. Bill Nazaroff, developed
this text through using experience from teaching CE 111, a junior-level undergraduate
environmental engineering class at UC Berkeley.
Selected Recent Publications
- Zeng, X., S.L. Simonich, K.L. Robrock, P. Korytár, L. Alvarez-Cohen, and D. F. Barofsky. 2008. “Development and validation of a congener specific photodegradation model for PBDEs”. Environmental Toxicology and Chemistry, in press.
- West, K. A., D. R. Johnson, P. Hu, T. Z. DeSantis, E. L. Brodie, P.K.H. Lee, H. Feil, G. L. Andersen, S. H. Zinder and L. Alvarez-Cohen. 2008. “Comparative Genomics of Dehalococcoides ethenogenes 195 and a Dehalococcoides-Containing Enrichment Culture”, Applied and Environmental Microbiology, Applied and Environmental Microbiology, in press.
- Johnson, D. R., E. L. Brodie, A. E. Hubbard, G. L. Andersen, S. H. Zinder, and L. Alvarez-Cohen . 2008. Temporal Transcriptomic Microarray Analysis of the Adaptation to Growth-Limiting Conditions in Dehalococcoides ethenogenes Strain 195, Applied and Environmental Microbiology, in press.
- Robrock, K., P. Korytár and L. Alvarez-Cohen. 2008. “Pathways for the Anaerobic Microbial Debromination of Polybrominated Diphenyl Ethers”, Environmental Science and Technology, in press.
- Lee, P. K. H., T. W. Macbeth, K. S. Sorenson and L. Alvarez-Cohen. 2008. “Quantifying Genes and Transcripts to Assess the In Situ Physiology of Dehalococcoides spp. in a Trichloroethene-Contaminated Field Site”, Applied and Environmental Microbiology, in press.
- Sharp, J. O., Sales, C.M., LeBlanc, J., Liu, J., Wood, T. K., Eltis, L.D., Mohn, W. W., and L. Alvarez-Cohen. 2007. “An Inducible Propane Monooxygenase is Responsible for N-nitrosodimethylamine Degradation by Rhodococcus sp. RHA1”, Applied and Environmental Microbiology, 73: 6930-6938.
- National Research Council Committee on Metagenomics (LA-C committee member) 2007. The New Science of Metagenomics: Revealing the Secrets of our Microbial Planet, National Academy Press, Washington DC.
- Mahendra, S., C.J. Petzold, E. E. Baidoo, J. D. Keasling and L. Alvarez-Cohen. 2007. “Identification of the Intermediates of in-vivo Oxidation of 1,4-Dioxane by Monooxygenase-Containing Bacteria”, Environmental Science and Technology, 41(21): 7330-7336.
- Lee, P. K. H., M. E. Conrad, and L. Alvarez-Cohen. 2007. “Stable Carbon Isotope Fractionation of Chloroethenes by Dehalorespiring Isolates”,Environmental Science and Technology, 41(12): 4277-4285.
- He, J., V. F. Holmes, P. K. H. Lee and L. Alvarez-Cohen. 2007. “Influence of Vitamin B12 and Co-cultures on the Growth of Dehalococcoides Isolates in Defined Medium”, Applied and Environmental Microbiology, 73 (9): 2847-2853.
- Lee, P.K.H., D.R. Johnson, V. F. Holmes, J. He and L. Alvarez-Cohen. 2006. “Reductive Dehalogenase Gene Experession as a Biomarker for Physiological Activity of Dehalococcoides spp. ”, Applied and Environmental Microbiology, 72 (9): 6161-6168.
- Holmes, V. F., J. He, P. K. H. Lee and L. Alvarez-Cohen. 2006. “Discrimination of Multiple Dehalococcoides Strains in a TCE Enrichment by Quantification of their Reductive Dehalogenase Genes”, Applied and Environmental Microbiology, 72 (9): 5877-5883.
- Lee, P. K. H., Johnson, D. R., Holmes, V. F., He, J , and L. Alvarez-Cohen. 2006. “Reductive Dehalogenase Gene Expression as a Biomarker for Physiological Activity of Dehalococcoides spp.”, Applied and Environmental Microbiology, 72 (9):6161-6168.
- He, J., K. R. Robrock and L. Alvarez-Cohen. 2006 “Microbial Reductive Debromination of Polybrominated Diphenyl Ethers (PBDEs)”, Environmental Science and Technology, 40 (14): 4429 -4434.
- Holmes, V. F., He, J, Lee, P. K. H., and L. Alvarez-Cohen. 2006. “Discrimination of Multiple Dehalococcoides Strains in a TCE Enrichment by Quantification of their Reductive Dehalogenase Genes”, Applied and Environmental Microbiology, 72 (9):5877-5883.
- Johnson, D. R., Lee, P. K. H., Holmes, V. F., and L. Alvarez-Cohen. 2005. “Transcriptional Expression of the tceA Gene in a Dehalococcoides-Containing Microbial Enrichment.”, Applied and Environmental Microbiology, 71 : 7145-7151.
- Freeborn R. A., V. K. Bhupathiraju, S. Chauhan, K. A. West,
B. G. Rahm, R. E. Richardson, L. Alvarez-Cohen. 2005. "Phylogenetic
Analysis of TCE-Dechlorinating Consortia Enriched on a Variety
of Electron Donors", Environmental Science and Technology, 39(21): 8358-8368.
- Johnson, D. R., Lee, P. K. H., Holmes, V. F., and L. Alvarez-Cohen.
2005. "An Internal Reference Technique for Accurately Quantifying
Specific mRNAs by Real-Time PCR with Application to the tceA Reductive
Dehalogenase Gene.", Applied and Environmental Microbiology, 71(7): 3866-3871.
- Rahm, B.G., Chauhan, S., Holmes, V.F., Macbeth, T W., Sorenson,
K. S., and L. Alvarez-Cohen. 2005. "Molecular Characterization
of Microbial Populations at Two Sites with Differing Reductive
Dechlorination Abilities.", Biodegradation,
17 (6): 523-534.
- Templeton, A. S., K-H Chu, L. Alvarez-Cohen, and M. E. Conrad.
2005. "Causes of variable Carbon Isotope Fractionation Exhibited
by Methane-Oxidizing Bacteria", Geochimica et Cosmochimica Acta, 70(2006): 1739-1752.
- Sharp, J. O., Wood, T.K. and L. Alvarez-Cohen. 2005. "Aerobic
Biodegradation of N-Nitrosodimethylamine (NDMA) by Axenic Bacterial
Cultures." Biotechnology and Bioengineering, 89(5): 608-618.
- Mahendra, S. and L. Alvarez-Cohen. 2005. "Pseudonocardia
dioxanivorans sp. nov., a Novel Actinomycete that Grows on 1,4-Dioxane."
International Journal of Systematic and Evolutionary Microbiology,
55: 593-598.
- National Research Council Committee on Source Removal of Contaminants
in the Subsurface (LA-C committee member) 2004. Contaminants in
the Subsurface: Source Zone Assessment and Remediation, National
Academy Press, Washington DC.
- Chu, K-H, S. Mahendra, D. L. Song, M. E. Conrad, and L. Alvarez-Cohen.
2004. "Stable Carbon Isotope Fractionation During Aerobic
Biodegradation of Chlorinated Ethenes". Environmental Science
and Technology, 38(11): 3126-3130.
- Deeb, R.A., K.H. Chu, T. Shih, S. Linder, M. Suffett, M. C.
Kavanaugh and L. Alvarez-Cohen. 2003. "MTBE and Other Oxygenates:
Environmental Sources, Analysis, Occurrence and Treatment".
Environmental Engineering Science, 20(5): 433-447.
- Mitch W.A., J.O. Sharp, R.R. Trussel, R.L. Valentine, L. Alvarez-Cohen,
and D.L. Sedlak. 2003. "N-Nitrosodimethylamine
as a Drinking Water Contaminant: A Review". Environmental Engineering
Science, 20(5): 389-404.
- Richardson, R. E., C. A. James, V. K. Bhupathiraju, and L.
Alvarez-Cohen. 2002. "Microbial Activity in Soils Following
Steam Treatment". Biodegradation, 13(4): 285-295.
- Richardson, R. E., V. K. Bhupathiraju, D. S. Song, T. Goulet,
and L. Alvarez-Cohen. 2002. "Phylogenetic Characterization
of Microbial Communities that Reductively Dechlorinate TCE Based
upon a Combination of Molecular Techniques". Environmental
Science and Technology, 36(12): 2652-2662.
- Song, D. L., M. E. Conrad, K. S. Sorenson, and L. Alvarez-Cohen.
2002. "Stable Carbon Isotope Fractionation During Enhanced
In-Situ Bioremediation of Trichloroethene". Environmental
Science and Technology, 36(10): 2262 -2268.
- Deeb, R. A., J. O. Sharp, A. Stocking, S. McDonald, K. A. West,
M. Laugier, P. J. J. Alvarez, M. C. Kavanaugh and L. Alvarez-Cohen.
2002. "Impact of Ethanol on Benzene Plume Lengths: Microbial
and Modeling Studies" ASCE Journal of Environmental Engineering,
128(9): 868-75.
- Bhupathiraju, V. K., P. Krauter, H-Y. N. Holman, M. E. Conrad,
P. F. Daley, A. S. Templeton, J. R. Hunt, M. Hernandez, and L.
Alvarez-Cohen. 2002. "Assessment of in-situ Bioremediation
at a Refinery Waste-Contaminated Site and an Aviation Gasoline
Contaminated Site", Biodegradation, 13(2): 79-90.
- Nazaroff, W. W, and L. Alvarez-Cohen. 2001. Environmental Engineering
Science , 690 pg. textbook, John Wiley and Sons, Collegiate Division,
ISBN 0-471-14494-0.
- Deeb, R.A., A. Stocking, L. Alvarez-Cohen, and M. C. Kavanaugh.
2001. "Biodegradability of Methyl Tert-Butyl Ether and Tert-Butyl
Alcohol", Chap. 16 in Oxygenates in Gasoline, Environmental
Aspects, A. F. Diaz and D. L. Drogos Eds., ACS Symposium Series
No. 799, American Chemical Society Books, ISBN: 0-8412-3760-3.
- Alvarez-Cohen, L., and G. E. Speitel. 2001. "Kinetics
of Aerobic Cometabolism of Chlorinated Solvents", Biodegradation,
12(2): 105-126.
- Deeb, R.A., H-Y Hu, J.R. Hanson, K.M. Scow, and L. Alvarez-Cohen.
2001. "Substrate
Interactions in BTEX and MTBE Mixtures by an MTBE-Degrading Isolate"
Environmental Science and Technology, 35(2): 312-317.
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